Beschreibung:
The book will be a rich source of information and instruction for oncologists and offers stimulating ideas on prospects for further progress in this field.
Describes current knowledge regarding pre-analytical issues of liquid biopsy
1. Introduction.- 2. Technical issue for implementation of liquid biopsy.- 3. Targets in circulation.- A. circulating tumour cells (CTCs).- B. circulating nucleic acid (ctDNA, cell free RNAs).- C. extracellular vesicles.- D. tumour educated platelets.- E. others (proteins, metabolites).- 4. Liquid biopsy as cancer screening: early cancer detection in general population.- 5. Liquid biopsy for patients with cancer.- A. treatment response monitoring.- B. MRD monitoring: early detection of recurrence.- C. Resistance mechanism tracking.- 6. Future perspectives.