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Neuroglia in Neurodegenerative Diseases
ISBN-13:
9789811399138
Veröffentl:
2019
Seiten:
405
Autor:
Alexei Verkhratsky
Serie:
1175, Advances in Experimental Medicine and Biology
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
Intended for researchers and students, the book presents recent advances concerning the biology of neuroglia as well as their interaction with neurons during disease progression. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Introduction to neuroglia: history, definition, development and main functions.- Evolution of astroglia.- Physiology of astroglia.- Glicoryne system: glial cells as secretory cells of the CNS.- Physiology of oligodendroglia and NG-2 glia.- Physiology of microglia.- General pathophysiology of neuroglia.- Neuroglia in ageing.- In vivo imaging of neuroglia in neurodegenerative diseases.- Astroglia in leukodystrophies.- Astrocytes in ALS.- Astroglia in Alzheimer's disease.- Oligodendrogia in Alzheimer's disease.- Microglia in AD.- Neuroglia in Parkinson's disease.- Neuroglia in Huntington disease.- Neuroglia as a therapeutic target.- Stem cell derived neuroglia: new tool for research and treatment of neurodegenerative diseases
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