This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein-protein interactions, gene expression and networks. The insights from these studies can be used in metagenomic data analysis and predicting artificial neural networks.

Includes well-illustrated chapters for easy understanding of methodologiesProvides the most recent research in the area of soft-computing analysisDiscusses how the insights from various computational studies can be collated and ultimately exploited practically

1. Diagnostic prediction based on gene expression profiles and artificial neural networks.- 2. Soft-Computing Approaches to Extract Biologically Significant Gene Network Modules.- 3. A Hybridization of Artificial Bee Colony with Swarming Approach of Bacterial Foraging Optimization for Multiple Sequence Alignment.- 4. Construction Gene Networks Using Gene Expression Profiles.- 5. Bioinformatics tools for shotgun metagenomic data analysis.- 6. Prediction of protein-protein interactions using machine learning techniques.- 7. Protein structure prediction using machine learning approaches.- 8. Drug-transporters as Therapeutic targets: Computational Models, Challenge and Opportunity.- 9. Module-Based Knowledge Discovery for Multiple-Cytosine-Variant Methylation Profile.- 10. Outlook of various soft computing data pre-processing techniques to study the pest population dynamics in Integrated Pest Management.- 11. Genomics for Oral Cancer Biomarker research.- 12. Soft-computing methods and tools for Bacteria DNA Barcoding data analysis.- 13. Fish DNA Barcoding: A comprehensive survey of the Bioinformatics tools and databases.