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Mechanisms of Gene Regulation
ISBN-13:
9789400779051
Veröffentl:
2013
Seiten:
210
Autor:
Carsten Carlberg
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines.
Overview: What is gene expression?.- The impact of chromatin.- The basal transcriptional machinery.- Transcription factors.- Linking signal transduction and gene regulation.- Switching genes on and off at the example of nuclear receptors.- Mapping the genome.- Chromatin modifiers.- Genomic imprinting.- The epigenome.- Chromatin remodeling.- Chromatin architecture.- Regulatory RNA.
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