Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and pub­ lished symposium lectures are often the best overviews available. Unfortu­ nately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung can­ cer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

I. Selected Topics.- 1. Role of natural killer (NK) cells in resistance to tumors.- 2. Clonal evolution and childhood tumors.- 3. Cancer cell differentiation.- 4. Clinical significance of chromosome abnormalities in childhood and adult leukemia.- II. Pancreatic Malignancies.- 5. Genetic aspects of endocrine neoplasia.- 6. Tumors of the exocrine pancreas in childhood.- 7. Pre-operative evaluation of pancreatic tumors.- 8. Surgical therapy in pancreatic malignancies in children.- 9. Pancreatic carcinoma in children in Japan-Review of the Japanese literature.- 10. Pancreatoblastoma. Histopathologic criteria based upon a review of six cases.- 11. Solid and papillary epithelial neoplasms of the pancreas.- 12. Ectopic Cushing's syndrome in an adolescent.- 13. Low grade papillary pancreatic neoplasm in an adolescent female.- 14. Cancer of the pancreas in children: Experience at the M.D Anderson Hospital and Tumor Institute.- 15. A case of metastatic insulinoma in an adolescent girl.- 16. Experience with endocrine and exocrine neoplasias in children.- 17. Childhood rare endocrine tumors.- 18. Overview of childhood pancreatic tumors.