Nowadays, we are dealing more frequently with the entity of large intestine polyps, as endoscopy and bowel cancer screening programmes are rapidly expanding. Often a single polyp is involved, but more complex situations are also encountered, including the well-defined pattern of polyposis. These situations can fall into a gray area, not only for diagnosis, but also for the correct treatment and follow-up. New developments in pathophysiology and treatment options are leading to new questions. This handbook aims to offer a integrated approach for all physicians (doctors) who deal with these issues, by presenting up-to-date discussion from genetics through treatment, to implications of genetic counseling. It will also help specialists to offer more "evidence-based" treatments, by implementing the best clinical individual judgement informed by the best current scientific evidence.

"Nowadays, we are dealing more frequently with the entity of large intestine polyps, as endoscopy and bowel cancer screening programmes are rapidly expanding. Often a single polyp is involved, but more complex situations are also encountered, including the well-defined pattern of polyposis. These situations can fall into a gray area, not only for diagnosis, but also for the correct treatment and follow-up. New developments in pathophysiology and treatment options are leading to new questions. This handbook aims to offer a integrated approach for all physicians (doctors) who deal with these issues, by presenting up-to-date discussion from genetics through treatment, to implications of genetic counseling. It will also help specialists to offer more "evidence-based" treatments, by implementing the best clinical individual judgement informed by the best current scientific evidence."

The Imapact of Bowel Cancer Screening.- Pathological Features of Sporadic Colonic Adenoma.- Serrated Neoplasia Pathway.- Genetic and Clinical Features of Familial Adenomatous Polyposis (FAP) and Attenuated FAP.- Not Only FAP Other Rare Polyposis Syndromes.- Diet, Polyps, and Cancer Where is the Truth?.- Chemoprevention of Colonic Cancer Is There a Foreseeable Future?.- The Role of Imaging in Colonic Polyps and Polyposis.- Rectal Polyps and Early Rectal Cancer Assessment by Three-Dimensional Endorectal Ultrasonography.- What is What? Clinical Vignettes of Multiple Polyps.- Diagnosis and Treatment of Upper Gastrointestinal Polyps in Polyposis.- Lower Gastrointestinal Endoscopy For Polyps and Polyposis.- Management and Treatment of Complications in Diagnostic and Therapeutic Lower Gastrointestinal Tract Endoscopy.- Follow-up After Endoscopic Polypectomy.- Surgical Options for Familial Adenomatous Polyposis.- Restorative Protocolectomy with Ileal Pouch- Anal Anastomosis for FAP.- Rectal Polyps after Ileorectal Anastomosis What is The Future?.- Anorectal Polyps and Polypoid Lesions.- Polypectomy of Anorectal Polyps and Polypoid Lesions Why, When, and How?.- Quality of Life and Familial Adenomatous Polyposis Patients.- Psychological and Medico-Legal Aspect of Genetic Counseling in Familial Adenomatous Polyposis.- The Role of a Registry in Familial Adenomatous Polyposis.- Coping With FAP The Roll of Patients' Associations.