Ameloblastomas are uncommon benign odontogenic neoplasms that rarely become malignant. In most cases, radical surgery is the treatment of choice for solid or multicystic ameloblastomas. Odontogenic tumors comprise a range of disorders of benign and malignant tissue which are formed by dental malformations. A good clinician should have a firm knowledge of oral pathologies, which is fundamental for understanding the intricate biological behavior of a particular group of lesions. The approach for the understanding of oral disease processes assists the clinician in the recognitions of specific conditions, and in the development of differential diagnosis, rational treatment and prognosis. Although several articles have been published on the subject, little is known regarding the biological behavior of this tumor. A careful clinical examination combined with a thorough imaging investigation to evaluate the general aspects of the lesions and its margins, as well as its internal architecture and its relationship to adjacent anatomical structures, can assist in treatment planning.