Human Factors Engineering Mutation and Hepcidin in Beta-Thalasseima
Thalassemia,Hfe gene,Hereditary hemochromatosis,iron metabolism,hepcidin
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ISBN-13:
9786202308939
Veröffentl:
2018
Einband:
Paperback
Erscheinungsdatum:
21.03.2018
Seiten:
140
Autor:
Sara Rabea Ibrahim Saad El-dien
Gewicht:
227 g
Format:
220x150x9 mm
Sprache:
Englisch
Beschreibung:
Thalassemia is an important hematological disorder. The possibility of iron overload development may be increase by Interaction between thalassemia and HFE gene mutations. This study aim to investigate the possible association between serum hepcidin level as indicator of iron concentration and the presence of HFE gene mutations. Excess iron overload increases the risk of liver cirrhosis,cancer,hypogonadism,arthritis, cardiac arrhythmia, heart failure, retinal degeneration, diabetes mellitus, neurodegenerative diseases (Alzheimer¿s,Parkinson¿s, Huntington¿s), and premature death.
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