Ethnopharmacological investigation of the spice Grewia paniculata
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ISBN-13:
9783659434532
Veröffentl:
2013
Einband:
Paperback
Erscheinungsdatum:
09.08.2013
Seiten:
104
Autor:
Mahmuda Nasrin
Gewicht:
173 g
Format:
220x150x7 mm
Sprache:
Englisch
Beschreibung:
The present study was carried out for pharmacological and chemical investigations on various crude extracts of Grewia paniculata bark and leaf. The phytochemical screening of all the extracts demonstrated the presence of carbohydrates, tannins, flavonoids, saponins, proteins, steroids and alkaloids. The analgesic activity was performed by acetic acid-induced writhing method, hot plate and tail immersion method in mice. The CNS depressant activity was evaluated by using hole cross, open field and thiopental induced sleeping time tests.The antidiarrhoeal activity was observed by castor oil induced diarrhoeal method. In brine shrimp lethality bioassay the extract exhibited moderate cytotoxic activity. In disc diffusion method the extracts displayed moderate activity against tested bacteria. These preliminary screening justify the traditional use of this medicinal plant.
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