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Inflammation and Gastrointestinal Cancers
ISBN-13:
9783642035036
Veröffentl:
2011
Seiten:
202
Autor:
Janusz A. Z. Jankowski
Serie:
185, Recent Results in Cancer Research
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
Inflammation in gastrointestinal mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it has fundamental clinical consequences, the principal of which is premalignant metaplasia throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for GI cancer.
Basic concepts of inflammation and its role in carcinogenesis.- Inherited syndromes predisposing to inflammation and GI cancer.- Stem cell biology and mucosal inflammation.- Acid reflux and esophageal cancer.- H Pylori and gastric cancer.- Inflammatory bowel disease and colon cancer.- Liver cancer.- Current screening strategies.- Targeted drug therapies and cancer.- Genetics of inflammation in the GI tract and how it can cause cancer.- Endoscopic methods.
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