Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI.

"Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI. TOC:An Overview of Contrast-Enhanced MRI in Oncology.- Contrast Agents for Magnetic Resonance Imaging.- The Role of Blood Pool Contrast Agents in the Study of Tumor Pathophysiology.- Dynamic Susceptibility Contrast-Enhanced MRI in Oncology.- Quantification of Contrast-Enhancement in Dynamic Studies.- Pharmacokinetic Modelling of Contrast Kinetics in Dynamic MR Studies.- Imaging Techniques: Imaging Techniques for Dynamic Contrast-Enhanced Imaging. Consensus Recommendations for Imaging in Angiogenesis.- Clinical Applications: Dynamic Magnetic Resonance Imaging in Cerebral Malignancy. Dynamic Magnetic Resonance Imaging in Breast Tumours. Dynamic Contrast Imaging in Cervical Carcinoma. Dynamic Contrast-Enhanced Imaging in the Prostate. Contrast-Enhanced MR Imaging in Musculoskeletal Tumors. Contrast-Enhanced MR Imaging in the Liver.- Applications: The Use of Dynamic Contrast-Enhanced MRI Multicentre Trials. Applications of Dynamic Magnet Resonance in Drug Development.- Subject Index."

Principles of Dynamic Contrast-Enhanced MRI.- An Introduction to Dynamic Contrast-Enhanced MRI in Oncology.- Contrast Agents for Magnetic Resonance Imaging.- The Role of Blood Pool Contrast Media in the Study of Tumor Pathophysiology.- Quantification of Dynamic Susceptibility Contrast T2* MRI in Oncology.- Measuring Contrast Agent Concentration in T1-Weighted Dynamic Contrast-Enhanced MRI.- Tracer Kinetic Modelling for T1-Weighted DCE-MRI.- Imaging Techniques.- Imaging Techniques for Dynamic Susceptibility Contrast-Enhanced MRI.- Consensus Recommendations for Acquisition of Dynamic Contrasted-Enhanced MRI Data in Oncology.- Clinical Applications.- Dynamic Contrast-Enhanced MRI in Cerebral Tumours.- Dynamic Magnetic Resonance Imaging in Breast Cancer.- Dynamic Contrast-Enhanced MR Imaging for Predicting Tumor Control in Patients with Cervical Cancer.- Dynamic Contrast-Enhanced MRI of Prostate Cancer.- Dynamic Contrast-Enhanced MR Imaging in Musculoskeletal Tumors.- Dynamic Contrast-Enhanced MRI in the Liver.- Applications.- Use of Dynamic Contrast-Enhanced MRI in Multi-Centre Trials with Particular Reference to Breast Cancer Screening in Women at Genetic Risk.- Applications of Dynamic Contrast-Enhanced MRI in Oncology Drug Development.