With contributions from a panel of experts representing a range of disciplines, this practical reference presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins.

Characterization of protein molecules prepared by total chemical synthesis Automated fast flow peptide synthesisN,S- and N,Se-acyl transfer devices in protein synthesisChemical synthesis of proteins through native chemical ligation of peptide hydrazidesExpanding native chemical ligation methodology with synthetic amino acid derivativesPeptide ligations at sterically demanding sitesControlling segment solubility in large protein synthesisTowards HPLC-free total chemical synthesis of proteinsSolid phase chemical ligationSer/Thr ligation for protein chemical synthesisProtein semisynthesis Bio-orthogonal imine chemistry in chemical protein synthesisDeciphering protein folding using chemical protein synthesisChemical synthesis of ubiquitinated proteins for biochemical studiesGlycoprotein synthesisChemical Synthesis of membrane proteins Chemical synthesis of selenoproteins Histone synthesisApplication of chemical synthesis to engineer protein backbone connectivityBeyond phosphate esters - synthesis of unusually phosphorylated peptides and proteins for proteomic researchCyclic peptides via ligation methods