Knapp und präzise erklärt dieses einführende Lehrbuch der Immunologie die Funktion des Immunsystems anhand sorgfältig ausgewählter Beispiele aus der klinischen Praxis und dem Experiment. Von Büchern mit ähnlichem Themenspektrum unterscheidet es sich durch den klar evidenzbasierten Ansatz. Die Autoren -- ein erfahrener Dozent und ein angesehener Forscher -- regen dabei stets zur kritischen Reflexion des gelernten Stoffs an.Based on examples using clinical and experimental data, this concise introductory textbook provides an insight into the immune system, prompting readers to ask critical questions in order to further advance our understanding.Website: wiley-vch.de/home/immunology

INTRODUCTIONIntroductionImmune ResponsesInfection and ImmunityImmunopathology and ImmunotherapyExploring ImmunologyTHE IMMUNE SYSTEMIntroductionHost Defence Against InfectionAnatomical Basis of ImmunityCellular Basis of ImmunityMolecular Basis of ImmunityImmune Responses and DiseaseINFECTION AND IMMUNITYIntroductionPathogens and Infectious DiseaseHost Defence Against InfectionInfection and Immunity in ActionImmunity and VaccinesFUNCTIONAL ANATOMY OF THE IMMUNE SYSTEMIntroductionNatural BarriersFunctional Anatomy of Innate ImmunityFunctional Anatomy of Adaptive ImmunityDevelopment of Blood Cells and Organs of ImmunityStem Cell and Gene TherapyINNATE IMMUNITYIntroductionInduction of Innate Immunity"Tissue-Resident Cells" of Innate ImmunityRecruited Effectors of Innate ImmunityHaematopoiesis and Myeloid CellsVaccines and AdjuvantsT CELL-MEDIATED IMMUNITYIntroductionMajor Histocompatibility Complex and Antigen PresentationT Lymphocyte ActivationEffector and Memory Functions of T Cells in InfectionT Cell Development and SelectionAdoptive Cell TherapyANTIBODY-MEDIATED IMMUNITYIntroductionAntibody Structure and FunctionB Cell ResponsesB Cell Memory, Antibodies and Long-Term Resistance to Re-InfectionCell Differentiation and SelectionTherapeutic AntibodiesIMMUNITY, DISEASE AND THERAPYIntroductionWhat are the Mechanisms of Tissue Damage Caused by the Immune System?Why Do We Make Harmful Immune Responses to Harmless Antigens?Immunopathology and Therapy in ActionTransplantation ImmunologyTumour ImmunityConclusionsANSWERS TO THE QUESTIONSFURTHER STUDY QUESTIONS