Presenting a wide variety of methods, this book provides a comprehensive overview of the current state -- ranging from bioanalysis to electrochemical sensing, forensics and chemistry, while also covering the toxicity aspects of nanomaterials to humans and the environment.Edited by rising stars in the field, the first section on biological analysis includes an investigation of nanoparticles and micro- and nanofluidic systems, while the second, environmental analysis, looks at the detection, monitoring, and sensing of explosives as well as pollutants, among other topics. The final part covers such advanced methods as the synthesis and characterization of gold nanorods. For analytical chemists, materials scientists, chemists working in trace analysis, and spectroscopists.

PrefacePART I: Biological and Chemical AnalysisPHOTOSWITCHABLE NANOPROBES FOR BIOLOGICAL IMAGING APPLICATIONSIntroductionPhotoswitchable Fluorescent NanoprobesPhotoswitchable Manetic NanoparticlesFuture PerspectivesAPPLICATIONS OF SEMICONDUCTOR QUANTUM DOTS IN CHEMICAL AND BIOLOGICAL ANALYSISIntroductionHistoryClassificationsCharacteristicsSynthesis and Surface ChemistryTrace Analysis Using Quantum DotsSummaryNANOMATERIAL-BASED ELECTROCHEMICAL BIOSENSORS AND BIOASSAYSIntroductionNanomaterial Labels Used in Electrochemical Biosensors and BioassaysNanomaterial-Based Electrochemical Devices for Point-of-Care DiagnosisConclusionsCHEMICAL AND BIOLOGICAL SENSING BY ELECTRON TRANSPORT IN NANOMATERIALSIntroductionElectron Transport through Metal NanoparticlesSensing Applications Based on Electron Transport in Nanoparticle AssembliesConcluding RemarksMICRO- AND NANOFLUIDIC SYSTEMS FOR TRACE ANALYSIS OF BIOLOGICAL SAMPLESIntroductionNucleic Acid AnalysisProtein AnalysisMicrofluidic Devices for Single-Cell AnalysisConclusionPART II: Environmental AnalysisMOLECULARLY IMPRINTED POLYMER SUBMICRON PARTICLES TAILORED FOR EXTRACTION OF TRACE ESTROGENS IN WATERIntroductionPrinciple of Molecular Recognition by ImprintingAnalytical Application of MIPs for Biopharmaceuticals and ToxinsPreparation of MIP Submicron ParticlesBinding Properties of MIP Submicron Particles with E2Trace Analysis of E2 in Wastewater TreatmentCurrent ProgressRecent Advances in MIP Technology for Continuing DevelopmentTRACE DETECTION OF HIGH EXPLOSIVES WITH NANOMATERIALSIntroductionTechniques for Trace Detection of High ExplosivesConclusionsNANOSTRUCTURED MATERIALS FOR SELECTIVE COLLECTION OF TRACE-LEVEL METALS FROM AQUEOUS SYSTEMSIntroductionSorbents for Trace-Metal Collection and Analysis: Relevant Figures of MeritThiol-Functionalized Ordered Mesoporous Silica for Heavy Metal CollectionSurface-Functionalized Magnetic Nanoparticles for Heavy Metal Capture and DetectionNanoporous Carbon Based Sorbent MaterialsOther Nanostructured Sorbent MaterialsConcluding ThoughtsSYNTHESIS AND ANALYSIS APPLICATIONS OF TiO2-BASED NANOMATERIALSIntroductionSynthesis of TiO2 NanostructuresApplications of TiO2-Based Nanomaterials for Chemical AnalysisConclusionsNANOMATERIALS IN THE ENVIRONMENT: THE GOOD; THE BAD, AND THE UGLYIntroductionThe Good: Nanomaterials for Environmental SensingThe Bad: Environmental Fate of NanomaterialsThe Ugly: Detection of Nanomaterials in the EnvironmentConclusionsPART III: Advanced Methods and MaterialsELECTROANALYTICAL MEASUREMENTS AT ELECTRODES MODIFIED WITH METAL NANOPARTICLESIntroductionModification of Electrodes with NanoparticlesGeometric Factors in Electrocatalysis by NanoparticlesAnalytical Applications of Electrodes Modified with Metal NanoparticlesConclusionsSINGLE MOLECULE AND SINGLE EVENT NANOELECTROCHEMICAL ANALYSISIntroductionBasic ConceptsSingle-Molecule ElectrochemistrySingle-Nanoparticle Electrochemical DetectionNanoelectrodes for Ultrasensitive Electrochemical Detection and High-Resolution ImagingElectrochemical Detection in Nanodomains of Biological SystemsLocalized Delivery and Imaging by Using Single Nanopipette-Based Conductance TechniquesANALYTICAL APPLICATIONS OF BLOCK COPOLYMER-DERIVED NANOPOROUS MEMBRANESIntroductionMonolithic Membranes Containing Arrays of Cylindrical Nanoscale PoresBCP-Derived Monoliths Containing Arrays of Cylindrical NanoporesSurface Functionalization of BCP-Derived Cylindrical NanoporesInvestigation of the Permeation of Molecules through BCP-Derived Nanoporous Monoliths and their Analytical ApplicationsConclusionsSYNTHESIS AND APPLICATIONS OF GOLD NANORODSIntroductionAu Nanorod SynthesisSignal EnhancementApplications of Au Nanorods in Trace AnalysisApplications of Au Nanorods in Other FieldsConclusions