Provides the tools and background for implementation of instrumental sample preparation workflow concepts for GC-MS and LC-MS analyses in the laboratory. The analytical advantages of its implementation and operational aspects during sample handling are discussed.

1. Introduction2. The Analytical Process2.1 Laboratory Logistics3. Workflow Concepts3.1 Sample Preperation Workflow Design3.2 Instrumental Concepts3.3 Sample Processing3.4 Tool Change3.5 Object Transport3.6 Vial Decapping4. Analytical Aspects4.1 Liquid Handling4.2 Solid Materials Handling4.3 Weighing4.4 Extraction4.5 Clean-Up Procedures4.6 Centrifugation4.7 Evaporation4.8 Deriatization4.9 Temperature Control4.10 Mixing5. Integration into Analysis Techniques5.1 GC Volatiles Analysis5.2 GC Liquid Injection5.3 LC-GC Online Injection5.4 LC Injection6. Solutions for Automated Analysis6.1 Dilution6.2 Derivatization6.3 Taste and Odor Compounds Trace Analysis6.4 Sulfur Compounds in Tropical Fruits6.5 Ethanol Residues in Halal Food6.6 Volatile Organic Compounds in Drinking Water6.7 Geosmin in 2-MIB6.8 Solvent Elution from Charcoal6.9 Semivolatile Organic Compounds6.10 Polyaromatic Hydrocarbons in Drinking Water6.11 Fatty Acid Methylester6.12 MCPD andGlycidol in Vegetable Oil6.13 Mineral Oil Hydrocarbons MOSH/MOAH6.14 Pesticides Analysis - QuEChERS Extract Clean-Up6.15 Glyphosate, AMPA, and Glufosinate by Online SPE-LC-MS6.16 Pesticides, PPCPs, and PAHs by Online SPE-Water Analysis6.17 Residual Solvents6.18 Chemical Warfare Agents in Water and Soil6.19 Shale Aldehydes in Beer6.20 Phthalates in PolymersA. AppendixA.1 Robotic System ControlA.2 System MaintenanceA.3 Syringe Needle GageA.4 Pressure Units ConversionA.5 SolventsA.6 Material Resistance