This is the 2nd edition of a very well received and popular book that reflects the current state-of-the-art of the ongoing research avenues concerning the hippocampus and processing units bridging the gap between single cell activity, network activity and global brain function. It aims to provide a methodology to anyone interested in developing microcircuit level models of the hippocampus.

Preface.- Experimental Background.- Connectivity of the hippocampus.- Morphology of hippocampal neurons.- Physiological properties of hippocampal neurons .- Glutamatergic Neurotransmission in the Hippocampus.- Fast and slow GABAergic transmission in hippocampal circuits.- Synaptic plasticity at hippocampal synapses - experimental background.- Neuromodulation of hippocampal cells and circuits.- cell type-specific activity during hippocampal network oscillations in Vitro.- Recording identified neurons in awake and anesthetized rodents.- Spatial, temporal, and behavioral correlates of hippocampal neuronal activity: A primer for computational analysis.- Computational Analysis.- Systematic data mining of hippocampal synaptic properties.- spatio-temporal patterns of granule cell activity revealed by a large-scale, biologically realistic model of the hippocampal dentate gyrus.- A model of spatial reach in LFP recordings.- Models of rate and phase coding of place cellsin hippocampal microcircuits.- A model for grid firing and theta-nested gamma oscillations in layer 2 of the medial entorhinal cortex.- computational models of grid cell firing .- Modeling synaptic plasticity in hippocampus: a calcium-based approach.-Simplified compartmental models of CA1 pyramidal cells of theta-modulated inhibition effects on spike timing-dependent plasticity .- Factors affecting STDP in the dendrites of CA1 pyramidal cells.- Computational examination of synaptic plasticity and metaplasticity in hippocampal dentate granule neurons .- Genome-wide associations of schizophrenia studied with computer simulation.- Modelling epileptic activity in hippocampal ca3.- A network model reveals that the experimentally observed switch of the granule cell phenotype during epilepsy can maintain the pattern separation function of the dentate gyrus.- Resources for modeling in computational neuroscience.- Experiment-modelling cycling with populations of multi-compartment models: application to hippocampal interneurons .- Index.