This is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors¿ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise. Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic.

First definitive text of total intravenous anesthesia and target controlled infusion

CONTENTSPART 1.  INTRODUCTION/BACKGROUND1. When and How Did It All Begin? A Brief History of Intravenous AnesthesiaJohn Sear2. The Development and Regulation of Commercial Devices for Target - Controlled Drug InfusionJohn B Glen3. The Memory Labyrinth: systems, processes and boundariesRobert A. Veselis4. Consciousness and AnaesthesiaRam Adapa5. Mechanisms of Intravenous Anaesthetic ActionHugh C. Hemmings Jr and Karl F. HeroldPART 2.  PRINCIPLES OF PHARMACOLOGICAL MODELING6. Basic Pharmacology: Kinetics and Dynamics for DummiesJohan Raeder7. Pharmacokinetic-Pharmacodynamic Modelling of Anesthetic DrugsJohannes Hans Proost8. Principles of Target Controlled InfusionsSteven L. Shafer9.  Performance of Target-Controlled Infusion SystemsMatthew TV Chan10. How to Select a PK/PD ModelKenichi MasuiPART 3.  PHARMACOLOGY OF THE INTRAVENOUS ANESTHETIC AGENTS11. Propofol PK-PDDouglas J. Eleveld12. Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral ActionsDouglas E. Raines13. Dexmedetomidine: The Science and Clinical Aspects in Adults and ChildrenMohamed Mahmoud14. Clinical Effects and Applications of KetamineMark G. Roback15. Neuromuscular Blocking Drugs: Pharmacology, Physiology and Clinical AspectsClaude Meistelman16. New and Upcoming Drugs: Intravenous Anesthetic Agents John William Sear17. Drug Interactions in AnesthesiaJaap VuykPART 4. PRACTICAL CONDUCT OF SEDATION AND ANESTHESIA18. Pumps Pitfalls and PracticalitiesFrank Engbers19. EEG Monitoring of Depth of AnesthesiaMichael Sury20. Monitoring the analgesic component of anesthesiaIsabelle Constant