This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ¿omics¿ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ¿omics sciences¿ with a special interest in dairy cattle health.

Discusses theory and application of systems biology approaches in dairy cattle health

Introduction.- A. Application of systems biology approach in diagnosis of periparturient disease.- 1. Metritis and fertility in transition dairy cows.- 2. Mastitis in transition dairy cows.- 3. Lameness and laminitis in transition dairy cows.- 4. Fatty liver in transition dairy cows.- 5. Milk fever in transition dairy cows.- 6. Displaced abomasum in transition dairy cow.- B. Application of systems biology approach in identification of screening biomarkers of diseases in transition dairy cows.- 7. Metritis and fertility in transition dairy cows.- 8. Mastitis in transition dairy cows.- 9. Lameness and laminitis in transition dairy cows.- 10. Fatty liver in transition dairy cows.- 11. Milk fever in transition dairy cows.- 12. Displaced abomasum in transition dairy cow.