|
| Der Artikel wird am Ende des Bestellprozesses zum Download zur Verfügung gestellt. |
Cell Division Machinery and Disease
ISBN-13:
9783319571270
Veröffentl:
2017
Seiten:
235
Autor:
Monica Gotta
Serie:
1002, Advances in Experimental Medicine and Biology
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal link between key elements of the cell division machinery and diseases such as cancer, neuropathologies, aging, and infertility. A more clinically oriented chapter further discusses the current and future applications of anti-mitotic drugs in these diseases. Cell Division Machinery and Disease is essential reading for graduate or advanced graduate students, researchers or scientists working on cell division as well as clinicians interested in the molecular mechanisms of the discussed diseases.
1.Meiotic divisions: no place for gender equality.- 2.Consequences of centrosome dysfunction during brain development.- 3.Dividing with extra centrosomes: a double edged sword for cancer cells.- 4.Kinetochore malfunction in human pathologies.- 5.The elephant in the room: the role of microtubules in cancer.- 6.Clinical development of anti-mitotic drugs in cancer.- 7.Mitotic dysfunction associated with aging hallmarks.- 8.Unbalanced Growth, Senescence and Aging.- 9.The spindle orientation machinery beyond mitosis: when cell specialization demands polarization.
Kunden Rezensionen
Mehr zum Thema
Folgen Sie uns auf:
