Beschreibung:
This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation "ketamine-like" fast-acting antidepressants.
1. History of Ketamine Use and its Clinical Indications.- 2. Basic and Clinical Pharmacology of Ketamine.- 3. Ketamine: Clinical Studies in Treatment-Resistant Depressive Disorders.- 4. Ketamine and Suicidality.- 5. Ketamine: Safety, Tolerability, and Impact on Neurocognition.- 6. Ketamine's Mechanisms of Rapid Antidepressant Activity: Evidence Gleaned from Pre-Clinical Studies.- 7. Ketamine's Mechanisms of Rapid Antidepressant Activity: Evidence Gleaned from Clinical Studies.- 8. Ketamine and Electroconvulsive Therapy.- 9. Beyond Depressive Disorders: Emerging Data for the Use of Ketamine in OCD, PTSD, and Alcohol/Substance Use Disorders.