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Models of Calcium Signalling
ISBN-13:
9783319296470
Veröffentl:
2016
Seiten:
436
Autor:
Geneviève Dupont
Serie:
43, Interdisciplinary Applied Mathematics
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
This book discusses the ways in which mathematical, computational, and modelling methods can be used to help understand the dynamics of intracellular calcium. The concentration of free intracellular calcium is vital for controlling a wide range of cellular processes, and is thus of great physiological importance. However, because of the complex ways in which the calcium concentration varies, it is also of great mathematical interest.This book presents the general modelling theory as well as a large number of specific case examples, to show how mathematical modelling can interact with experimental approaches, in an interdisciplinary and multifaceted approach to the study of an important physiological control mechanism.
Some Background Physiology.- The Calcium Toolbox.- Basic Modeling Principles: Deterministic Models.- Hierarchical and Stochastic Modeling.- Nonlinear Dynamics of Calcium.- Nonexcitable Cells.- Muscle.- Neurons and Other Excitable Cells.
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