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Pharmacological Assays of Plant-Based Natural Products
ISBN-13:
9783319268118
Veröffentl:
2015
Seiten:
188
Autor:
Thangaraj Parimelazhagan
Serie:
71, Progress in Drug Research
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
This volume provides information on howto select and screen plants for their medicinal properties. It describes phytopharmacologicaltechniques for extracting and qualitatively and quantitatively analyzing aplant's phytochemicals. After a detailed in vitro investigation including nutritionaland anti-nutritional analyses, medicinal properties were tested with various invivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer andanti-diabetic properties, as well as wound healing, neurodegenerative diseasesetc. Compound identification and purification techniques include, among othersTLC and column chromatography, as well as molecular docking with specificproteins.
1. Extraction of plant material.- 2. Critical aspects of purification and impurities in natural product extracts. 3. In vitro antioxidant assays.- 4. In vivo antioxidant assays.- 5. Quantification assays.- 6. Anti-nutritional factors.- 7. Anti-inflammatory activity.- 8. Antipyretic activity.- 9. Inflammation bowel disease.- 10. Anti-arthritic activity.- 11. Evaluation of analgesic potential.- 12. Anti-diarrhoeal activity.- 13. Anti-ulcer activity.- 14. In vitro anti-diabetic activity.- 15. In vivo anti-diabetic activity.- 16. Hepatoprotective property.- 17. Antitumor activity.- 18. In vivo wound healing studies.- 19. Determination of cytotoxicity.- 20. Evaluation of bioavailability.- 21. Molecular identification by DNA barcoding.- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.
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