This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow¿s generation of life-saving cardiac devices.

Includes companion videos that visualize functional cardiac anatomy jointly developed by the University of Minnesota and the Cardiac Rhythm Management Division at Medtronic, Inc.

Foreword.- Preface.- Part I. Introduction.- 1. General Features of the Cardiovascular System.- Part II. Anatomy.- 2. Attitudinally Correct Cardiac Anatomy.- 3. Cardiac Development.- 4. Anatomy of the Thoracic Wall, Pulmonary Cavities and Mediastinum.- 5. Anatomy of the Human Heart.- 6. Comparative Cardiac Anatomy.- 7. Detailed Anatomical and Functional Features of the Cardiac Valves.- 8. The Coronary Vascular System and Associated Medical Devices.- 9. The Pericardium.- 10. Congenital Cardiac Anatomy and Operative Correction.- 11. Mechanical Circulatory Support Devices Pediatric Patients.- Part III. Physiology and Assessment.- 12. Cellular Myocytes.- 13. The Cardiac Conduction System.- 14. Autonomic Nervous System.- 15. Cardiac and Vascular Receptors and Signal Transduction.- 16. Reversible and Irreversible Damage of the Myocardium: Ischemia/Reperfusion Injury and Cardioprotection.- 17. The Effects of Anesthetic Agents on Cardiac Function.- 18. Blood Pressure, Heart Tones, and Diagnoses.- 19. Basic ECG Theory, 12-lead Recordings and their Interpretation.- 20. Mechanical Aspects of Cardiac Performance.- 21. Fueling Normal and Diseased Hearts-Myocardial Bioenergetics.- 22. Introduction to Echocardiography.- 23. Monitoring and Managing the Critically Ill Patient in the Intensive Care Unit .- 24. Cardiovascular Magnetic Resonance Imaging and MRI-conditional Cardiac Devices.- Part IV. Devices and Therapies.- 25. Historical Perspective of Cardiovascular Devices and Techniques associated with the University of Minnesota.- 26. Pharmacotherapy for Cardiac Diseases.- 27. Animal Models for Cardiac Research.- 28. Catheter Ablation of Cardiac Arrhythmias.- 29. Cardiac Ablative Technologies.- 30. Pacing and Defibrillation.- 31. Cardiac Resynchronization Therapy.- 32. Cardiac Mapping Technology.- 33. Cardiopulmonary Bypass and Cardioplegia.- 34. Heart Valve Disease.- 35. Less Invasive Cardiac Surgery.- 36. Transcatheter Valve Repair and Replacement.- 37. Cardiac SeptalDefects: Treatment via the Amplatzer® Family of Devices.- 38. Harnessing Cardiopulmonary Interactions to Improve Circulation and Outcomes after Cardiac Arrest and Other States of Low Blood Pressure.- 39. : End-stage Congestive Heart Failure in the Adult Population: Ventricular Assist Devices.- 40. Cell Transplantation for Ischemic Heart Disease.- 41. The Use of Isolated Heart Models and Anatomic Specimens as Means to Enhance the Design and Testing of Cardiac Devices.- 42. Current Status of Development and Regulatory Approval of Cardiac Devices.- 43. Clinical Trial Regulations for Cardiac Devices.- Cardiac Devices and Technologies: Continued Rapid Rates of Development.- Index.