This book is the first of its kind and is useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.

Preface.- Foreword.- Section 1. Fundamentals.- Chapter 1. Introduction: The Case for Endoradiotherapy.- Chapter 2. The History of Endoradiotherapy.- Chapter 3. The Nuclear Chemistry of Therapeutic Radionuclides.- Chapter 4. The Production of Therapeutic Radionuclides.- Chapter 5. The Radiobiology of Alpha Particles, Beta Particles, and Auger Electrons.- Chapter 6. The Radiopharmaceutical Chemistry of Metallic Radionuclides.- Chapter 7. The Radiopharmaceutical Chemistry of Non-Metallic Radionuclides.- Chapter 8. Dosimetry in Endoradiotherapy.- Section 2. Deeper Dives.- Chapter 9. Antibodies as Vectors for Endoradiotherapy.- Chapter 10. Case Study #1: 225Ac-Labeled IgG.- Chapter 11. Case Study #2: 131I-3F8.- Chapter 12. Case Study #3: Antibody Fragments in Endoradiotherapy.- Chapter 13. Peptides as Vectors for Endoradiotherapy.- Chapter 14. Case Study #4: LUTATHERA.- Chapter 15. Case Study #5: CXCR4.- Chapter 16. Case Study #6: JR11.- Chapter 17. Small Molecules as Vectors for Endoradiotherapy.- Chapter 18. Case Study #7: PSMA-617.- Chapter 19. Case Study #8: 223RaCl3.- Section 3. Special Topics.- Chapter 20. Auger Emitters in Endoradiotherapy.- Chapter 21. In Vivo Pretargeting.- Chapter 22. Theranostic Imaging and Endoradiotherapy.- Chapter 23. The Next Generation of Therapeutic Radionuclides.- Chapter 24. Artificial Intelligence and Machine Learning.- Chapter 25. The Regulatory Review of Radiotherapeutics: USA.- Chapter 26. The Regulatory Review of Radiotherapeutics: Europe.- Chapter 27. The Regulatory Review of Radiotherapeutics: Japan.- Chapter 28. Radiotherapeutics in the Nuclear Pharmacy.- Chapter 29. The Future.