This new edition fully updates and expands Faro and Mohamed's Functional Neuroradiology, a gold standard, comprehensive introduction to the state-of-the-art functional imaging in neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging.

Part I Diffusion and Perfusion Imaging.- Physical Principles of Diffusion Imaging.- Clinical Applications of Diffusion.- Physical Principles of MR Perfusion and Permeability Imaging: Gadolinium Bolus Technique.- Non-gadolinium Perfusion Technique (Arterial Spin Labeling).- Clinical Applications of MR Perfusion Imaging.- Stroke: Clinical Application of Perfusion and Diffusion.- Clinical Applications of Dynamic Contrast-Enhanced (DCE) Permeability Imaging.- Part II Magnetic Resonance Spectroscopy.- Magnetic Resonance Spectroscopy: Physical Principles.- Magnetic Resonance Spectroscopy: Clinical Applications.- Part III Multi Modality Functional Neuroradiology.- Functional Imaging-Based Diagnostic Strategy: Intra-axial Brain Masses.- Functional Neuroimaging of Epilepsy.- Functional Neuroradiology of Traumatic Brain Injury.- Functional MRI of Multiple Sclerosis.- Functional Neuroradiology of Psychiatric Diseases.-Neuroimaging of Pain.- Part IV BOLD Functional MRI: Physical Principles.- Principles of BOLD Functional MRI.- fMRI Scanning Methods.- Experimental Design and Data Analysis for fMRI.- Challenges in fMRI and Its Limitations.- Neurovascular Uncoupling in Functional MR Imaging.- Functional Connectivity MR Imaging.- Clinical Challenges of Functional MRI.- Part V BOLD Functional MRI: Clinical Applications.- fMRI of Language Systems: Methods and Applications.- Functional MRI Studies of Memory in Aging, Mild Cognitive Impairment, and Alzheimer's Disease.- fMRI Wada Test: Prospects for Presurgical Mapping of Language and Memory.- fMRI of Human Visual Pathways.- Brain Mapping for Neurosurgery and Cognitive Neuroscience.- Pediatric Applications of fMRI.- fMRI of the Central Auditory System.- fMRI of Epilepsy.- Applications of fMRI to Psychiatry.- Applications of fMRI to Neurodegenerative Disease.- Applications of MRI to Psychopharmacology.- Functional MRI: Cognitive Neuroscience Applications.- Part VI Diffusion Tensor Imaging.- Diffusion Tensor Magnetic Resonance Imaging: Physical Principles.- Issues in Translating Imaging Technology and Presurgical Diffusion Tensor Imaging.- White Matter: Functional Anatomy of Key Tracts.- Epilepsy: Clinical Applications of Diffusion Tensor Imaging.- DTI and fMRI: Review of Complementary Techniques.- Part VII Beyond Proton Imaging. Magnetoencephalography: Epilepsy and Brain Mapping.- PET-CT/MR Imaging in Head and Neck Cancer: Physiologic Variations, Pitfalls, and Directed Applications.- Simultaneous PET and MR Imaging of the Human Brain.- The Role of Molecular Imaging in Personalized Medicine.- Metabolic Magnetic Resonance Imaging: A Case for Bioscales in Medicine.- Part VIII Functional Spine and CSF Imaging.- Functional MRI of the Spinal Cord: Diffusion-Weighted, Diffusion Tensor Imaging, and Fiber Tractography.- MRI of Hydrocephalus and CSF Velocity Imaging.- Part IX: Neuroanatomical Brain Atlas.- Neuroanatomical Atlas of Key Presurgical and Cognitive Eloquent Cortex Regions.- Normal Anatomic Atlas of Common White Matter Tracts Using DTI.- fMRI Paradigms.- Part X: Major Advancements.- Diffusion kurtosis (DKI) and Neurite Orientation Dispersion and Density Imaging (NODDI):Principles and Emerging clinical applications.- Radiogenomics of Brain Tumors: Principles and clinical emerging clinical applications.- Autism: Review of Functional Neuroradiology research and emerging clinical applications.- Traumatic Brain Injury: Review of Functional Neuroradiology research and emerging clinical applications.- Alzheimer's Dementia: Review of Functional Neuroradiology research and emerging clinical applications.- Chemical Exchange Saturation Transfer MR Imaging (CEST): Principles and emerging clinical applications.-Resting State fMRI: Principles and clinical applications.- Phase Contrast CSF flow of the brain: Principles and clinical applications.- Brain and Spine Tractography: Principles and Clinical applications.- Machine Learning.