This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.

Section I: Introduction to Rapid On-Site Evaluation.- Overview.- Facility, Equipment, Specimen Preparation, and Stains.- Section II: Biopsies of Superficially Located Organs with or without Imaging Guidance.- Thyroid.- Breast.- Salivary Gland.- Lymph Node.- Section III: Image-Guided Biopsies of Deep-Seated Organs.- Liver.- Kidney and Adrenal Gland.- Bone and Soft Tissue.- Section IV: Bronchoscopy-Guided Biopsies.- Lung.- Mediastinum.- Section V: Endoscopy-Guided Biopsies.- Pancreas.- Gastrointestinal Tract.- Section VI: Evolving Concepts of Rapid On-Site Evaluation.- Cytological Evaluation during Intraoperative Consultation.- Economics, Regulations, and Trends in Place.- Telecytopathology.