Providing the first comprehensive book on the current state of hyperpolarized xenon-129 NMR and MRI, this book is guaranteed to appeal to a wide range of scientists interested in this growing field. It is also intended to create synergy between the various (sub)-communities working with this noble gas.

Xenon as a Probe Atom: Introduction, Characteristics, Investigation of Microporous Solids; The Xenon Chemical Shift and Chemical Shift Anisotropy; Spin Exchange Optical Pumping (SEOP) - Concepts and Practical Considerations; Optimization of Pump Cells: Simulation and Experiments; Large Volume and Continuous Flow Hyperpolarization; Spin-Exchange Optical Pumping at High Xenon Densities and Laser Fluxes: Principles and Practice; T1 Relaxation of 129Xe and How to Keep It Long; Hyperpolarized 129Xe NMR in Materials Sciences: Pore Structure, Interconnectivity and Functionality; Porous Materials Explored by Hyperpolarized Xenon NMR; Xenon Porometry; HP Xe-129 NMR Characterization of Single-File Diffusion in Nanotubes; Studies of Metal-Organic Frameworks: Xenon for Probing Framework Porosity, Breathing and Gating Behavior; Hyperpolarized Xenon Biosensors and HyperCEST; Biosensing and Study of Biological Cells Using Hyperpolarized 129Xe; Cryptophane-Based 129Xe NMR Biosensors; Caged Xenon in Phospholipid Membrane Environments; Continuous Flow and Dissolved Phase 129Xe NMR/MRI for Quantification in Preclinical Study as well as Materials Science; Hyperpolarized Xenon-129 Gas Uptake in the Human Lung and XTC MRI; Xenon Septal Uptake; 129Xe Chemical Shift and Spin-lattice Relaxation Dependences on Blood Oxygenation; Transverse Relaxation of 129Xe in the Lung; Magnetic Resonance Imaging of the Brain using Hyperpolarized 129Xe; Beyond Spin I = ¿ - Hyperpolarized 131Xe and 83Kr Magnetic Resonance; Beyond Spin Exchange Optical Pumping: Hyperpolarization of 129Xe via Sublimation Dynamic Nuclear Polarization; Rethinking the Detection Scheme: Hyperpolarized Xenon NMR and MRI Signal Amplification by Gas Extraction and Remote Detection; Subject Index