Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable.

Positron Emission Tomography in Clinical Medicine.- Physics and Instrumentation in PET.- Data Acquisition and Performance Characterization in PET.- Image Reconstruction Algorithms in PET.- Quantitative Techniques in PET.- Tracer Kinetic Modeling in PET.- Coregistration of Structural and Functional Images.- Anato-Molecular Imaging: Combining Structure and Function.- Radiohalogens for PET Imaging.- Progress in 11C Radiochemistry.- Metal Radionuclides for PET Imaging.- Radiation Dosimetry and Protection in PET.- Whole-Body PET Imaging Methods.- Artefacts and Normal Variants in Whole-Body PET and PET/CT Imaging.- The Technologist's Perspective.- PET Imaging in Oncology.- The Use of Positron Emission Tomography in Drug Discovery and Development.- PET as a Tool in Multimodality Imaging of Gene Expression and Therapy.