An examination of the research and translational application to prevent and treat biofilm-associated diseasesIn the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense.Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically,Microbial Biofilms provides* state-of-the-art research in the field of bacterial and fungal biofilms* detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms* future areas of research and their translational and clinical applicationsMicrobial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.

ContributorsPrefaceAcknowledgments1 New Technologies for Studying Biofilms2 Fungal Biofilms: In Vivo Models for Discovery of Anti-Biofilm Drugs3 Biofilm Development4 Division of Labor in Biofilms: the Ecology of Cell Differentiation5 Candida albicans Biofilm Development and Its Genetic Control6 Candida Biofilms: Development, Architecture, and Resistance7 Biofilm Formation by Cryptococcus neoformans8 Aspergillus Biofilm In Vitro and In Vivo9 Adhesins Involved in Attachment to Abiotic Surfaces by Gram-Negative Bacteria10 Biofilm Matrix Proteins11 Bacterial Extracellular Polysaccharides in Biofilm Formation and Function12 The Biology of the Escherichia coli Extracellular Matrix13 Antimicrobial Tolerance in Biofilms14 How Biofilms Evade Host Defenses15 c-di-GMP and its Effects on Biofilm Formation and Dispersion: a Pseudomonas Aeruginosa Review16 Mechanisms of Competition in Biofilm Communities17 Dispersal from Microbial Biofilms18 Chemical Biology Strategies for Biofilm Control19 From Biology to Drug Development: New Approaches to Combat the Threat of Fungal BiofilmsIndex