In the aftermath of World War II, the members of the Sutton family are reeling from the death of their "golden boy," Eddie. Over the next twenty-five years, they all struggle with loss, grief, and mourning. Daughter Harriet and son Nat attempt to fill the void Eddie left behind: Harriet becomes a chemist despite an inhospitable culture for career women in the 1940s and '50s, hoping to move into the family business in New Jersey, while Nat aims to be a jazz musician. Both fight with their autocratic father, George, over their professional ambitions as they come of age. Their mother, Eleanor, who has PTSD as a result of driving an ambulance during the Great War, wrestles with guilt over never telling Eddie about the horrors of war before he enlisted. As the members of the family attempt to rebuild their lives, they pay high prices, including divorce and alcoholism-but in the end, they all make peace with their losses, each in his or her own way.