Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting 5-10% of children and adolescents and 3% of adults. In Attention Deficit Hyperactivity Disorder: From Genes to Patients, expert psychiatrists, psychologists, pharmacologists, and pharmaceutical scientists from around the world comprehensively review all critical aspects of our latest understanding of ADHD. The authors emphasize the evaluation and treatment of patients with ADHD, moving from the day-to-day approach by the clinical psychologist to the more sophisticated anatomical and functional imaging strategies that have emerged in the last decade. Specific impairments, such as reading disabilities, social difficulties, and limited working memory are analyzed in detail, as well as for their respective contributions to global functioning. Additional chapters explain, in a readable style, current theories on the pathophysiology of ADHD, focusing on neurotransmitters and the insights gained from animal models. An expanded review of the pharmacotherapy of ADHD includes appropriate methods for selecting of specific drugs for individual patients based on drug kinetics and gene expression.Comprehensive and state of the art, Attention Deficit Hyperactivity Disorder: From Genes to Patients offers pediatricians, psychologists, and psychiatrists an authoritative guide to understanding the pathophysiology, symptomatology, evaluation, and treatment of patients with ADHD.

Includes supplementary material: sn.pub/extras

Historical Aspects of Attention Deficit Hyperactivity Disorder.- Scanning the Genome for Attention Deficit Hyperactivity Disorder.- Dopamine Knockouts and Behavior.- The Spontaneously Hypertensive Rat as a Model of Attention Deficit Hyperactivity Disorder.- The Roles of Norepinephrine and Serotonin in Attention Deficit Hyperactivity Disorder.- Intermittent Hypoxia During Sleep as a Model of Environmental (Nongenetic) Contributions to Attention Deficit Hyperactivity Disorder.- The Psychological Evaluation of Attention Deficit Hyperactivity Disorder in School-Aged Children.- Executive Function.- The Neuropsychology of Attention Deficit Hyperactivity Disorder.- Attention Deficit Hyperactivity Disorder and Learning Disabilities.- Selective Attention Deficits in Children with Attention Deficit Hyperactivity Disorder.- Working Memory in Children with ADHD.- Developmental Underpinnings of the Association of Attention Deficit Hyperactivity Disorder and Its Subtypes to Neuropsychological and Academic Weaknesses.- Social Functioning of Children With Attention Deficit Hyperactivity Disorder.- Reading Disabilities in Children With Attention Deficit Hyperactivity Disorder.- Attention Deficit Hyperactivity Disorder and the Brain.- Anatomical and Functional Neuroimaging Studies of Children and Adolescents With Attention Deficit Hyperactivity Disorder.- State Regulation and Attention Deficit Hyperactivity Disorder.- Sleep and Attention Deficit Hyperactivity Disorder.- Neuropsychological Performance in Adults With Attention Deficit Hyperactivity Disorder.- Psychostimulants in Attention Deficit Hyperactivity Disorder.- Pharmacokinetic and Pharmacodynamic Drug Interactions.