Pharmacokinetics in Drug Discovery and Development
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ISBN-13:
9781566769730
Veröffentl:
2002
Erscheinungsdatum:
06.03.2002
Seiten:
440
Autor:
Ronald D Schoenwald
Gewicht:
794 g
Format:
244x166x30 mm
Sprache:
Englisch
Beschreibung:
The field of pharmacokinetics has become increasingly specialized in the last ten years. So much so that few individuals are fully knowledgeable in every subspecialty. Pharmacokinetics in Drug Discovery and Development provides the ideal comprehensive, quick access text/reference. Formatted for easy access to the information, the book provides description, cause, and assessment in bulleted lists with a minimum of verbiage provide a breadth of topic coverage and in a convenient size so that readers can find their information fast. The book serves as a resource that relates terminology, concepts, and approaches linking the subspecialties of pharmacokinetics.
BASIC PRINCIPLES: Basic Principles. INDUSTRIAL AND REGULATORY APPLICATIONS: PK/PD Approach. Pharmacokinetics and Metabolism in Drug Discovery and Preclinical Development. Phase I, II, and III FDA Submissions. Bioavailability and Bioequivalence. CLINICAL APPLICATIONS: General Approaches to Clinical Pharmacokinetic Monitoring. Aminoglycosides and Other Antibiotics. Cardiovascular Agents. Psychotropic Agents. Theophylline. Anticonvulsant Agents. RESEARCH APPLICATIONS: Classical Modeling. Non-compartmental Modeling. Physiologically-Based Pharmacokinetic Models. Population Pharmacokinetics. The Linear Systems Approach.
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