|
| Der Artikel wird am Ende des Bestellprozesses zum Download zur Verfügung gestellt. |
Signaling Mechanisms Regulating T Cell Diversity and Function
ISBN-13:
9781498705097
Veröffentl:
2017
Seiten:
274
Autor:
Jonathan Soboloff
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
T cell origins, interactions and roles in adaptive immunity. Mechanisms regulating progression through DN stages. Positive selection. Negative selection. ThPok in cd4/cd8 selection. Directing cells into Gamma/Delta variants. Tregs. iNKT. Early events in T cell receptor engagement. T cell engagement and the Immunological Synapse. Orai1-mediated Ca2+ entry and T cell activation. Transcriptional mechanisms modulating Ca2+ signals during T cell activation. IFNs and Differentiation to Th1 cells.
Kunden Rezensionen
Mehr zum Thema
Folgen Sie uns auf:
