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Biophysics of RNA-Protein Interactions
ISBN-13:
9781493997268
Veröffentl:
2019
Seiten:
249
Autor:
Chirlmin Joo
Serie:
Biological and Medical Physics, Biomedical Engineering
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more.
Part 1: RNA Binding Proteins.- Chapter 1: How proteins recognize RNA.- Chapter 2: The interaction between L7Ae family of proteins and RNA kink turns.- Chapter 3: Evolving methods in defining the role of RNA in RNP assembly.- Chapter 4: Single-molecule studies of exonuclease: Following cleavage actions one step at a time.- Chapter 5: Fitting in the age of single-molecule experiments: A guide to maximum-likelihood estimation and its advantages.- Part II: Transcription and Translation.- Chapter 6: A single-molecule view on cellular and viral RNA synthesis.- Chapter 7: Single-Molecule Optical Tweezers Studies of Translation.- Part III: RNA-Guided Protein Machineries.- Chapter 8: Biophysical and biochemical approaches in the analysis of Argonaute-miRNA complexes.- Chapter 9: Biophysics of RNA-guided CRISPR immunity.- Chapter 10: Dynamics of MicroRNA Biogenesis.
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