Beschreibung:
This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research.
Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the experts
sp. from Prion Positive Eye Tissues of Sheep Affected with Terminal Scrapie.- Detection and Diagnosis of Prion Diseases using RT-QuIC: An Update.- Analysis of Charge Isoforms of the Scrapie Prion Protein using Two-Dimensional Electrophoresis.- Exosomes in Prion Diseases.- Synthetic Mammalian Prions.- Biomarkers in Cerebrospinal Fluid.- The Use of Transgenic and Knock Out Mice in Prion Research.- Transgenic Mouse Models of Prion Diseases.