Previously considered rare, Peyronie's disease affects nearly 10% of adult men. Recent advances in wound-healing disorders have substantially increased the understanding of Peyronie's disease and its pathophysiology. In Peyronie's Disease: A Guide to Clinical Management, international authorities review the current nonsurgical and surgical therapeutic options for dealing with this fibrotic disorder. A variety of state-of-the-art research techniques is discussed, including tissue analysis, cell culture of fibroblasts derived from Peyronie's plaques, and animal models that attempt to mimic the in vivo process of tunica albuginea fibrosis while also providing an opportunity for manipulation with novel therapeutic techniques.Although there is no cure for Peyronie's diseases, this text discusses treatments that may result in physical improvement or help to stabilize the scarring process. For those with a more advanced disease, surgical options to correct the deformity in an effort to make the patients functional again are reviewed. Also discussed are the many misconceptions about Peyronie's disease, so that a practicing physician will be able to diagnose, treat, or refer the patient more appropriately.As the first medical text on the subject, Peyronie's Disease: A Guide to Clinical Management provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease as well as presents a review of the available medical and surgical treatment options.

Previously considered rare, Peyronie's disease affects nearly 10% of adult men. Recent advances in wound-healing disorders have substantially increased the understanding of Peyronie's disease and its pathophysiology. In Peyronie's Disease: A Guide to Clinical Management, international authorities review the current nonsurgical and surgical therapeutic options for dealing with this fibrotic disorder. A variety of state-of-the-art research techniques is discussed, including tissue analysis, cell culture of fibroblasts derived from Peyronie's plaques, and animal models that attempt to mimic the in vivo process of tunica albuginea fibrosis while also providing an opportunity for manipulation with novel therapeutic techniques. Although there is no cure for Peyronie's diseases, this text discusses treatments that may result in physical improvement or help to stabilize the scarring process. For those with a more advanced disease, surgical options to correct the deformity in an effort to make the patients functional again are reviewed. Also discussed are the many misconceptions about Peyronie's disease, so that a practicing physician will be able to diagnose, treat, or refer the patient more appropriately.As the first medical text on the subject, Peyronie's Disease: A Guide to Clinical Management provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease as well as presents a review of the available medical and surgical treatment options.

Table of Contents for Peyronie's disease Textbook:Introduction Laurence A. Levine M.D.1. Historical review of Peyronie's disease: de la Peyronie to Devine Emre Akkus M.D.2. Epidemiology of Peyronie's disease Ates Kadioglu M.D. and Oner Sanli M.D.3. Experimental models for the study of the cellular and molecular pathophysiology of Peyronie's disease Nestor F Gonzalez-Cadavid Phd and Jacob Rajfer Phd.4. The clinical implications of basic science research in Peyronie's disease. John P. Mulhall.5. Evaluation of the man with Peyronie's disease Jason M Greenfield, M.D. and Laurence A. Levine, M.D.6. Oral Therapy-Peyronie's Disease - Levine April 1st 2005. Claudio Teloken M.D, Tulio Graziottin M.D and Patrick Teloken M.D.7. Intralesional treatment of Peyronie's disease Muammer Kendririci M.D , London Trost M.D and Wayne J. G. Hellstrom M.D.8. Topical therapy: Iontophoresis and Electromotive Drug Administration Savino M. Di Stasi M.D, Antonella Giannantoni M.DEmmanuele A. Jannini M.D, Giuseppe Vespasiani M.DLuigi Storti M.D , Francesco Attisani M.D and Robert L. Stephen¿9. Topical therapy for Peyronie's disease: Ultrasound, laser, gels/creams/solutions Paul F. Engelhardt M.D and Claus R. Riedl M.D.10. Combination non-surgical therapy Vincenzo Mirone M.D11. Extracorporeal shock wave therapy (ESWT) in Peyronie's disease Ekkehard W. Hauck M.D and Wolfgang Weidner M.D.12. The Nesbit and plication procedures for Peyronie's disease David Ralph M.D.13. Penile Plication using the 16-Dot TechniqueRobert C. Dean, M.D. and Tom F. Lue, M.D.14. Penile Straightening with Tunica Albuginea Plication - TAP Procedure Laurence A. Levine, M.D.15. Incisional corporoplasty for thecorrection of Peyronie's disease caused penile curvature Daniel Yachia M.D.16. Peyronie's disease: Surgical straightening with tunica plication and tunica transfer Dimitros G. Hatzichristou M.D and Konstantinos Hatzichristou M.D, PhD.17. A review of plaque incision with focus on temporalis fascia grafts Martin Gelbard18. Venous patch graft surgery for Peyronie's disease Robert C. Dean M.D and Tom F. Lue M.D.19. Use of Porcine Small Intestinal Mucosal Graft in the Surgical Management of Peyronie's Disease L. Dean Knoll M.D.20. Penile Straightening with Plaque Incision or Partial Excision and Human Pericardial Grafting Technique Laurence A. Levine, M.D.21. Surgical straightening with tunica incision and grafting technique (Single relaxing incision based on geometrical principles) Paulo Egydio M.D.22. Minimally invasive intracorporal incision of Peyronie's plaque Anthony J. Bella M.D and Gerald B. Brock M.D23. Surgical straightening with penile prosthesis Culley Carson M.D and Steve Wilson M.D.