Epigenetic Methods in Neuroscience Research

.105, Neuromethods
 Previously published in hardcover
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Includes cutting-edge methods and protocols
Daniel L. Ross and Garrett A. Kaas
This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system. Epigenetic Methods in Neuroscience Research  guides readers through methods for the analyses of chromatin remodeling, transposable elements, non-coding RNAs, such as miRNAs, and circadian oscillations, including: analysis of DNA methylation in neuronal and glial cells or small tissue samples; sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry; affinity-based detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation; chromatin immunoprecipitation, or ChIP; miRNA high-throughput profiling and the in situ detection of miRNA subtle expression in the brain; analysis of genes with alternative 3'UTRs; and the cite-specific delivery of chromatin-modifying drugs. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

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Autor: Nina Karpova
ISBN-13 :: 9781493949410
ISBN: 1493949411
Verlag: Springer, Berlin, Springer New York, Humana Press
Gewicht: 617g
Seiten: 258
Sprache: Englisch
Auflage Softcover reprint of the original 1st ed. 2016
Sonstiges: Taschenbuch, 254x178x mm, 6 SW-Abb., 37 Farbabb., 16 Tabellen
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