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Cholesterol Transporters of the START Domain Protein Family in Health and Disease
ISBN-13:
9781493911127
Veröffentl:
2014
Seiten:
190
Autor:
Barbara J. Clark
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:
Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer, and atherogenesis.
An Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-related Lipid Transfer Domain Protein Family.- The Steroidogenic Acute Regulatory Protein (StAR).- START domain protein structure and ligand specificity.- Congenital Lipoid Adrenal Hyperplasia.- Steroidogenic Acute Regulatory protein (StAR) and Atherogenesis.- STARD3: a lipid transfer protein in breast cancer and cholesterol trafficking.- The STARD4 subfamily: STARD4 and STARD5 in cholesterol metabolism.- START proteins in non-vesicular cholesterol transport.- Index.
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