Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases.This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by organ system. All other texts in the field, which are now quite old, are arranged according to specific fungi. Organization by body system rather than fungi is important because one particular fungus can have a different effect on defense mechanisms in different parts of the body.

Fungal Immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases.

PrefaceContributors Section 1 - Nasal Cavity1. Fungal Sinusitis; Tobias E. Rodriguez, Jack R. Harkema, and Gary B. Huffnagle Section 2 - Oral Cavity2. Innate Defense Mechanisms in Oral Candidiasis; Anna Dongari-Bagtzoglou3. Humoral Factors in the Protection of the Oral Cavity against Candidiasis; Stephen J. Challacombe, Durdana Rahman, Mukesh Mistry, and Julian A. Naglik4. Oral Candidiasis: Clinical Manifestations and Cellular Adaptive Host Responses; Robert B. Ashman and Camile S. Farah Section 3 - Lungs5. The Innate and Adaptive Immune Response to Pulmonary Histoplasma capsulatum Infection; George S. Deepe, Jr.6. Lung Immunity to Blastomyces dermatitidis Infection; Marcel Wüthrich and Bruce S. Klein7. Innate Immunity in the Lungs to Cryptococcal Infection; Kazuyoshi Kawakami8. Pulmonary Cell-Mediated Immunity (CMI) to Cryptococcus neoformans; Dennis M. Lindell and Gary B. Huffnagle9. Antibody-Mediated Immunity to Fungi in the Lungs; Marta Feldmesser and Arturo Casadevall10. Pulmonary Paracoccidioidomycosis; Vera L.G. Calich and Maria H.S.L. Blotta11. The Innate and Acquired Pulmonary Immune Response to Aspergillus fumigatus; Jane M. Schuh and Cory M. Hogaboam12. Fungal Hypersensitivity in the Lungs; Viswanath P. Kurup and Alan P. Knutsen13. Immunology of Pulmonary Pneumocystis Infection: Cell-Mediated Immunity; Judd E. Shellito and James M. Beck14. Antibody-Mediated Immunity to Pneumocystis in the Lungs; Beth A. Garvy and Francis Gigliotti Section 4 - Gastrointestinal Tract15. Innate and Adaptive Immunity against Candida species infections in the Gastrointestinal Tract; Robert D. Wagner Section 5 - Vaginal Tract16. Innate and Adaptive Cell-Mediated Immunity against Vaginal Candidiasis; Paul L. Fidel Jr.17. The Role of Humoral Immunity against Vaginal Candida Infection; Flavia De Bernardis, Maria Boccanera, and AntonioCassone Section 6 - Blood18. Role of Complement in Fungal Infections; Thomas R. Kozel19. Innate and Adaptive Immunity to Systemic Candida albicans Infection; Luigina Romani20. Interactions of Fungi with Endothellal Cells; Scott G. Filler and Donald C. Sheppard Section 7 - Skin21. Immunology of Cutaneous Candidiasis; Srividya Srinivasan, David K. Wagner, and Peter S. Sohnle22. Immune Surveillance against Dermatophyte Infection; Tetsuya Koga23. Immune Surveillance against Sporothrix schenckii infection; Takeshi Uenotsuchi, Tetsuo Matsuda, Masutaka Furue, and Tetsuya Koga Section 8 - Central Nervous System24. Innate and Acquired Immunity in Cryptococcus neoformans Infections of the Central Nervous System; Kent BuchananIndex