Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part B is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems. This collection deals with surgery involving the respiratory, cardiovascular, skeletal, gastrointestinal, genital, and central nervous systems of the test animals. One paper describes the procedures to be followed in thoracic incisions, emphasizing the importance of access to airways and parenchymal resections. In explaining cardiovascular surgery, one paper details the specialized surgical equipment, anesthesia, blood flow, and post-operative care that the test animal needs. Another paper describes the procedures and techniques, as well as limb immobilization or total joint prostheses that should be followed in a surgery involving the skeletal system. One author also considers in detail both research surgeries of the male and female reproductive tracts. The paper on surgery involving the peripheral and central nervous system gives general techniques used in chronic studies of such system. Veterinarians, laboratory workers dealing with test animals, and researchers designing animal and medical experiments will find this book very informative.

ForewordPrefaceChapter 1 Surgery of the Respiratory System I. Introduction II. Thoracic Incisions for Model Preparations III. Access to Airways and Parenchymal Resections IV. Models for Measurement of Lung Fluid and Protein Flux ReferencesChapter 2 Cardiovascular Surgery for Chronic Experimentation in Conscious Animals I. Introduction II. Hemodynamic Measurements III. Surgical Equipment and Instruments IV. Preoperative Care V. Anesthesia VI. Thoracic Surgery VII. Instrumentation of the Thoracic Cavity VIII. Dimensions IX. Blood Flow X. Abdominal Surgery XI. Surgical Techniques to Interrupt the Neural Control of the Cardiovascular System XII. Vascular Surgery XIII. Postoperative Care ReferencesChapter 3 Experimental Surgery of the Skeletal System I. Introduction II. Special Considerations in Species Selection III. Procedures and Techniques IV. General Postoperative Considerations V. Limb Immobilization: External Coaptation VI. Specific Animal Models VII. Total Joint Prostheses ReferencesChapter 4 The Gastrointestinal Tract I. Introduction II. Cannulas Used for Chronic Preparations III. Esophageal Preparation IV. Surgical Preparations for the Study of Gastric Function V. Preparations for the Study of Pancreatic Function VI. Preparations for the Study of Biliary Function VII. Intestinal Preparations VIII. Miscellaneous References Chapter 5 Experimental Surgery of the Genital System I. Introduction II. Selection of Animal Models III. Technical Considerations in Genital Surgery IV. Research Surgery of the Male Reproductive Tract V. Research Surgery of the Female Reproductive Tract ReferencesChapter 6 Peripheral and Central Nervous System I. Introduction II. Peripheral Nervous System III. Central Nervous System ReferencesIndex