Current Topics in Cellular Regulation, Volume 14 reviews the advances in the general area of cellular regulation.This book discusses the mechanism and function of the C4 pathway, regulation of individual enzymes, inhibitors of isoleucine and valine biosynthesis, and patterns of derepression. The functions of 2,3-bisphosphoglycerate; 2,3-bisphosphoglycerate in erythrocytes during development; and regulation of glycogen synthetase activity are also elaborated. This publication likewise covers the substrate specificity of cAMP-dependent protein kinase, model systems of enzyme sequences, and posttranslational modifications in selected enzymes.This volume is a good source for biologists and researchers interested in the basic mechanisms involved in the regulation of diverse cellular activities.

List of ContributorsRegulation of Enzymes in C4 Photosynthesis I. Introduction II. Mechanism and Function of the C4 Pathway III. Regulation of Individual Enzymes IV. Other Aspects of Regulation ReferencesRegulation of Isoleucine and Valine Biosynthesis I. Introduction II. Gene-Enzyme Relationship III. Specialized Plasmids IV. Regulation of the Metabolic Flow of Intermediates V. Patterns of Derepression VI. Inhibitors of Isoleucine and Valine Biosynthesis VII. The Corepressor Problem VIII. Gene Expression IX. Multiple Regulatory Mechanisms ReferencesFunctions of 2,3-Bisphosphoglycerate and Its Metabolism I. Introduction II. Historical Remarks III. Occurrence of 2,3-Bisphosphoglycerate IV. Functions of 2,3-Bisphosphoglycerate V Control of 2,3-Bisphosphoglycerate Metabolism VI. 2,3-Bisphosphoglycerate in Erythrocytes During Development ReferencesThe Role of Cyclic-AMP-Dependent Protein Kinase in the Regulation of Glycogen Metabolism in Mammalian Skeletal Muscle I. Introduction II. Discovery of the Glycogenolytic Cascade and cAMP-Dependent Protein Kinase III. The Regulation of Phosphorylase Kinase Activity IV. The Regulation of Glycogen Synthetase Activity V. The Regulation of Protein Phosphatase Activity VI. The Regulation of Protein Phosphatase 1 by Heat-Stable Inhibitor Proteins VII. The Substrate Specificity of cAMP-Dependent Protein Kinase VIII. The Substrate Specificity of Protein Phosphatases 1 and 2 IX. The Components of the Protein-Glycogen Complex ReferencesImmobilized Model Systems of Enzyme Sequences I. Introduction II. Naturally Occurring Systems of Enzyme Sequences III. Model Systems of Enzyme Sequences IV. On the Relevance of Immobilized Enzyme Sequences as Biological Models for Naturally Occurring Systems (Microenvironmental Compartmentation) V. Practical Applications of Immobilized Enzyme Sequences ReferencesPosttranslational Modifications of Enzymes I. Introduction II. Alterations of Enzymes in Selected Systems III. Posttranslational Modifications in Selected Enzymes IV. General Mechanisms V. Conclusion VI. Summary List of Abbreviations ReferencesSubject IndexContents of Previous Volumes