Advances in Physiological Sciences, Volume 29: Gastrointestinal Defence Mechanisms is a collection of papers that details the findings of research studies on the theoretical and practical aspects of the gastrointestinal defense mechanisms. The title first covers circulation and mucosal defense, and then proceeds to tackling the association of gastrointestinal mechanisms with the secretory functions. Next, the selection deals with the resistance in gastric mucosa and mucosal energy provision. The text also discusses cell renewal and toxicity, along with biotransformation and nutrition. In Part VII, the title details the immunomechanisms of defense at mucosa. The last part covers the second line defense at liver and enterohepatic circulation. The book will of great interest to both researchers and practitioners of medical fields concerned with the digestive system.

PrefaceWelcoming AddressCirculation and Mucosal Defense Circulatory Responses to Changes of Intestinal Contents The Role of the Microcirculation in the Gastrointestinal Defense Mechanism Impaired Defense Mechanism to Peptic Ulcer in the Capsaicin-Desensitized RatDefense and Secretory Functions Pseudocholinesterase Activity in Human Oral Fluid Regulation of Water Flux across Isolated Gastric Mucosa Test of Connection between Hypersecretion Produced Extragastric Stimulus and Sodium Metabolism Effect of Somatic Stimulus on the Acid Secretion Activity in Male and Female Rats Role of the Functional State of the Gastric Mucosa in Relation to Development of Epinephrine Effects on Rat Stomach The Effects of Atropine, Carbenoxolone, Atropine plus Carbenoxolone on the Gastric Acid Secretion and on the Aspirin-Induced Mucosal Damage in Rats Role of the Acute Starvation on the Development of Different Experimental Ulcers in the Rat Analysis of the Inhibitory Effect of Pelsonin (1:10 Combination of Indomethacin and Sodium-Salicylate) on Shay-Ulcer The Effect of Intraduodenal Hypertonic Glucose on the Gastric Mucosal BarrierResistance in Gastric Mucosa Gastric Mucosal Resistance to Physical and Chemical Stress Pathophysiology of Gastrointestinal Mucins The Effect of Different Prostaglandins on Restrain Ulcer of Rat Is Cyclic AMP the Mediator of Cytoprotection by Prostaglandins in Human Gastric MucosaMucosal Energy Provision Gastric and Small Intestinal Energy Metabolism in Mucosal Damage Biochemical Aspects of Cytoprotective Effect of Prostacyclin on the Rats' Gastric Mucosal Damage Induced By Topical HCl Effect of Noise Exposure on the Phosphate Metabolism of Gastric MucosaCell Renewal and Toxicity The Three-Compartmental Enzyme System of the Enterocyte Relating to Its Digestive and Barrier Functions The Effect of Cytostatics on Intestinal Protein Loss in Rats Biological Model System for Investigating Gastrointestinal Side Effects Caused By Cytostatic Agents Effect of Dianhydrogalactitol on Biochemical and Morphological Characteristics of the Rat Intestinal MucosaBiotransformation and Nutrition Mucosal Biotransformation and Metabolic Gradients in the Intestine Adaptation of Intestinal Biotransformation to Nutritional Variation Use of Explant Cultures to Study the Metabolism of Polycyclic Aromatic Hydrocarbons in the Human Gastrointestinal Tract The Activity of Epoxidehydratase in Human Colon from Biopsy Tissues Effect of Polycyclic Aromatic Hydrocarbons on Carboxylesterase Activity in Rat Liver and Duodenum Drug Metabolizing Enzyme Activities in Rats Exposed to Chlorinated Phenols Xenobiotic Metabolism in Rainbow Trout IntestineImmunomechanisms on Defense at Mucosa The Role of the Microbial Flora in the Development, Maintenance and Modulation of Host Immune Functions Immune Regulation Function of Gastrointestinal Tract. Disorders with Connection of Impaired Immune Regulation The Local Immunity Is a Part of the Gastrointestinal Defense Mechanism Some Antimicrobial Defense Mechanisms of the Upper Digestive TractSecond Line Defense at Liver and Enterohepatic Circulation Biliary Excretion of Xenobiotics Fecal Excretion of Digitoxin Metabolites in Germfree (GF) and Conventional (CV) RatsEffect of D-Glucaro-L,4-Lactone and Antibiotic Ingestion on the Fecal Excretion of Imipramin and Iopanoic AcidIndex