Reflecting the large and growing pedagogical landscape in the field, this new edition contains nearly double the number of chapters of its predecessor, making it approximately twice the length while incorporating new topics. Fully updated, it remains the only book that combines and integrates an extensive set of subjects in genetics and evolution in a manner that is readily understood by students at either the graduate or undergraduate level. It provides the basic foundations of molecular evolution, including the structure and function of macromolecules such as DNA, RNA, and proteins.

LIFE AND EVOLUTION. Definitions of Life. Earth and Evolution. BIOMOLECULES. DNA, RNA, and Proteins. The Central Dogma and Beyond. Ribosomes and Ribosomal RNA. Structure of the Genetic Code. DNA Replication. DNA Segregation. GENETICS. Mendelian and Non-Mendelian Characters. Population Genetics. Alleles through Time. Changes to DNA. Infectious Changes to DNA: Viruses, Plasmids, Transposons, and Introns. MULTICELLULARITY. Multigene Families. Horizontal Gene Transfer. Development: Part I-Cooperation Among Cells. Development: Part II-Plants. Cancer. MOLECULAR BIOLOGY AND BIOINFORMATIC METHODS. Extraction and Quantification of Biological Molecules. Recombinant DNA and Characterization of Biological Molecules. Sequencing and Alignment Methods. OMICS: Part I. OMICS: Part II. Species Concepts and Phylogenetics. Phylogenetic Networks and Reticulate Evolution. Phylogenomics and Comparative Genomics. GENOMES. RNA Viruses. DNA Viruses. Bacteria and Archaea. Mutualists and Pathogens. Endosymbionts and Organelles. Protein Trafficking. Eukaryotic Genomes. Human Genome.