Since the third edition of The Fundamentals of Nuclear Pharmacy was pub­ lished in 1992, radiopharmaceutical chemistry and various aspects of nuclear medicine have experienced significant growth and development. The new information plus the appreciation of the book in the nuclear medicine community have prompted us to publish a new edition. As with the past editions, this fourth edition is primarily based on the contents of various courses given over several decades to nuclear pharmacy students, nuclear medicine and radiology residents, and nuclear medicine technology students. The book is written in chronological order from the basic atomic structure to the clinical uses of radiopharmaceuticals. It serves as a textbook on nuclear pharmacy for nuclear pharmacy and nuclear medi­ cine technology students as well as a reference book for many professionals interested in nuclear medicine, such as nuclear medicine physicians and radiologists. There are 15 chapters in the book. At the end of each chapter a set of pertinent questions and some suggested reading materials are included.

1 The Atom.- 2 Radioactive Decay.- 3 Instruments for Radiation Detection and Measurement.- 4 Production of Radionuclides.- 5 Radionuclide Generators.- 6 Radiopharmaceuticals and Methods of Radiolabeling.- 7 Characteristics of Specific Radiopharmaceuticals.- 8 Quality Control of Radiopharmaceuticals.- 9 Nuclear Pharmacy.- 10 Internal Radiation Dosimetry.- 11 Radiation Regulations and Protection.- 12 In Vitro and In Vivo Nonimaging Tests.- 13 Diagnostic Uses of Radiopharmaceuticals in Nuclear Medicine.- 14 Therapeutic Uses of Radiopharmaceuticals in Nuclear Medicine.- 15 Adverse Reactions to and Altered Biodistribution of Radiopharmaceuticals.- Appendix A Abbreviations Used in Text.- Appendix B Terms Used in Text.- Appendix C Units and Constants.- Appendix F Answers to Questions.