Introduction. Nature of the HF/E Profession Today. Ergonomics and Ergonomists': Lessons for HF/E Practice from the Past and Present. The Nitty-Gritty of Human Factors. Human Factors and the Ethics of Explaining Failure. Human Factors and Ergonomics in the Media. HF/E Practitioner Roles. HF/E Practitioner Contexts. Integrating Research into Practice in HF/E. The Challenges of Practice-Oriented Research. HF/E Methods in Practice: The Right Tool for the Right Job. Becoming an HF/E Practitioner. HF/E Practice in Aviation: Assisting Human Performance in Aviation Operations. HF/E Practice in the Rail Industry: The Right Way, the Wrong Way and the Railway. HF/E Practice in the Oil & Gas Industry: Capital Projects and Human Capital. Human Factors in Healthcare. Challenges and Opportunities. HF/E Practice in the Nuclear Industry: Helping to Deliver Safety in a High-Hazard Industry. HF/E Practice in Military Aviation: On Time and on Target. HF/E in the Construction and Demolition Industry. HF/E Practice in Manufacturing: Integration in the Engineering Design Processes. HF/E Practice in user Experience: Demonstrating Value in a Fast-Growing Field. HF/E Practice for Consumer Product Design: Differentiating Products by Better Design. HF/E Practice in Web Engineering and Operations. HF/E Practice in Inclusive Design: making Accessibility Mainstream. HF/E Practice in Agriculture: The Challenges of Variety and Complexity. Selling 'Ergonomic' Products: Different Approaches for Different Applications. Human and Organisational Factors in Regulation: Views from a Former Regulator. Communicating with Decision Makers: Getting the Board on Board. Engaging Participants in Human Factors and Ergonomics. Writing as an HF/E Practitioner. Public and Social Media Engagement for HF/E Practitioners: Outreach, Research and Networking. Afterword.