James J. Goedert and a team of leading experimental and clinical researchers provide critical, integrating surveys of those viruses, bacteria, and parasites that are now known to play a major role in cancer-work that opens the way toward novel therapeutic targets. The contributors focus on five types of human carcinogenic infection-herpesviruses, retroviruses, papillomaviruses, hepatitis viruses, and H. pylori-and review in depth the associated malignancies, as well as how these new diagnostic and therapeutic technologies may be implemented. Cutting-edge and cross-disciplinary, Infectious Causes of Cancer: Targets for Intervention provides clinical oncologists and infectious disease specialists, as well as clinical researchers, with insightful reviews of cancer induction by infectious diseases and the high promise of closely targeted new therapeutics and vaccines.

Includes supplementary material: sn.pub/extras

I Background.- 1 History of Infectious Disease Oncology, from Galen to Rous.- II Herpesviruses.- 2 Overview of Herpesviruses.- 3 X-Linked Lymphoproliferative Disease.- 4 Posttransplant Lymphoproliferative Disorder.- 5 Epstein-Barr Virus and Burkitt's Lymphoma.- 6 Epstein-Barr Virus and Nasopharyngeal Carcinoma.- 7 Hodgkin's Disease.- 8 AIDS-Related Lymphoma.- 9 Leiomyoma and Leiomyosarcoma.- 10 Kaposi's Sarcoma and Other HHV-8-Associated Tumors.- III Retroviruses.- 11 Retroviruses and Cancer.- 12 Adult T-Cell Leukemia/Lymphoma.- 13 Clonal HIV in the Pathogenesis of AIDS-Related Lymphoma: Sequential Pathogenesis.- IV Papillomaviruses.- 14 Papillomaviruses in Human Cancers.- 15 Anogenital Squamous Cell Cancer and Its Precursors: Natural History, Diagnosis, and Treatment.- 16 Human Papillomaviruses and Cancers of the Skin and Oral Mucosa.- V Hepatitis Viruses.- 17 Overview of Hepatitis B and C Viruses.- 18 Hepatocellular Carcinoma.- 19 Hepatitis C Virus, B-Cell Disorders, and Non-Hodgkin's Lymphoma.- VI Bacterial and Helminthic Oncology.- 20 Overview of Helicobacter pylori.- 21 Gastric Adenocarcinoma.- 22 Gastric Mucosa-Associated Lymphoid Tissue Lymphoma.- 23 Salmonella typhi/paratyphi and Gallbladder Cancer.- 24 Schistosoma hematobium and Bladder Cancer.- VII Other Infections and Human Neoplasms.- 25 Does Childhood Acute Lymphoblastic Leukemia Have an Infectious Etiology?.- 26 Polyoma Viruses (JC Virus, BK Virus, and Simian Virus 40) and Human Cancer.- 27 In Pursuit of a Human Breast Cancer Virus, from Mouse to Human.