This volume contains reviews which are based on a symposium, given th at the 30 meeting of The Phytochemical Society of North America, held at Laval University in Quebec City, Canada on August 11-15, 1990. During the past two decades, there have been major new developments in methods which can be applied toward the isolation, separation and structure determination of complex natural products. Therefore, the topic of this symposium, "Modem Phytochemical Methods", is a very timely one. The organizers of the symposium recognized that it would not be possible to cover in detail all new advances in phytochemical methodology. It was therefore decided to emphasize general reviews on recent developments of major separation techniques such as high performance liquid chromatography as well as supercritical fluid chromato­ graphy. In addition, advances in commonly used structure determination methods, mainly NMR and MS, are reviewed. Other topics include methodo­ logies of micro-sampling for isolation and analysis of trichome constituents as well as recent breakthroughs on biosynthetic studies of monoterpenes using "enriched" basal cells of trichomes. The volume concludes with a review of quantitative structure-activity relationship (QSAR) studies of biologically active natural products. In Chapter I, K. Hostettmann and his colleagues give a general review of recent developments in the separation of natural products with major emphasis on preparative separations of biologically active plant constituents. The authors present a comparison of droplet countercurrent chromatography (OCCC) with the highly rapid and more versatile centrifugal partition chromatography (CPC).

Springer Book Archives

1. New Developments in the Separation of Natural Products.- 2. Recent Advances in High-Performance Liquid Chromatography of Volatile Natural Products.- 3. Enantioselective Separations in Phytochemistry.- 4. Supercritical Fluid Chromatography for the Analysis of Natural Products.- 5. Immobilized Artificial Membrane Chromatography.- 6. Mass Spectrometry in the Chemistry of Natural Products.- 7. Structure Elucidation of Natural Products by Mass Spectroscopy.- 8. Modern NMR Methods in Phytochemical Studies.- 9. Trichrome Microsampling of Sesquiterpene Lactones for the Use of Systematic Studies.- 10. Biosynthetic Methods for Plant Natural Products: New Procedures for the Study of Glandular Trichrome Constituents.- 11. Quantitative Structure-Activity Relationship Analysis of Natural Products: Phototoxic Thiophenes.