Beschreibung:
Designed for graduate and advanced undergraduate courses, this book goes beyond the simple analysis of naming a drug or toxin, taking a mechanistic approach to their effects on the body. It provides an understanding of the mechanisms of action of drugs and toxins as well as their physiologic and pathologic consequences on the affected organ system. Case histories, photographs of gross pathology, and photomicrographs further illustrate the processes and effects of toxic substances on the body.
PART I. Introduction. A Selected History of Forensic Toxicology. Toxicity and Toxidromes. Toxicokinetics. Biotransformation. Postmortem Toxicology. PART II. Neurotoxicology. Cardiac Toxicology. Hepatotoxicity. Kidney Toxicology. Pulmonary Toxicology. PART III. Alcohols: Ethanol, Methanol, and Related Compounds. Opiates and Opioids. Non-Opiate Sedative/Hypnotic Drugs. Sympathomimetic Amines: Amphetamines and Related Compounds. Hallucinogens, Psychedelics, and Cannabinoids. Cholinergic and Anticholinergic Toxins. Metals.