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Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
ISBN-13:
9781466556270
Veröffentl:
2014
Seiten:
260
Autor:
Chul Ahn
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
This book explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. For clustered studies, the authors provide sample size formulas that account for variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas that account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the authors describe how randomization impacts trial administration, analysis, and sample size requirement.
Sample Size Determination for Independent Outcomes. Sample Size Determination for Clustered Outcomes. Sample Size Determination for Repeated Measurement Outcomes Using Summary Statistics. Sample Size Determination for Correlated Outcome Measurements Using GEE. Sample Size Determination for Correlated Outcomes from Two-Level Randomized Clinical Trials. Sample Size Determination for Correlated Outcomes from Three Level Randomized Clinical Trials.
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