Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement
An Applied Approach Using SAS & Stata
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ISBN-13:
9781466505476
Veröffentl:
2015
Erscheinungsdatum:
04.12.2015
Seiten:
313
Autor:
Iftekhar Khan
Gewicht:
633 g
Format:
246x164x22 mm
Sprache:
Englisch
Beschreibung:
This guide explains how to apply health economic evaluation techniques to both clinical trial and non-clinical trial data. Through a simple, applied approach using examples and SAS software, the book helps statisticians and researchers in health economics assess cost-effectiveness. It covers trial design, case report form design, quality of life measures, sample sizes, submissions to regulatory authorities for reimbursement, Markov models, cohort models, and decision trees. Examples and case studies are provided at the end of each chapter.
Introduction to Economic Evaluation. Health Economic Evaluation Concepts. Designing Cost-Effectiveness into a Clinical Trial. Analyzing Cost Data Collected in a Clinical Trial. Quality of Life in Economic Evaluation. Modelling in Economic Evaluation. Sensitivity Analyses. Sample Size and Value of Information for Cost-Effectiveness Trials. Mixed Treatment Comparisons, Evidence Synthesis. Cost-Effectiveness Analyses of Cancer Trials. The Reimbursement Environment. References. Bibliography. Index.
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